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    CUTANA™ CUT&RUN Protocol

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    Question? Tech Support Center

    Current Protocol

    • April 10, 2023 v2.1

    Previous Versions

    • April 10, 2023 v2.0
    • April 10, 2023 v1.9
    • April 10, 2023 v1.8

    Related Products

    CUT&RUN Kit

    The CUTANA™ CUT&RUN Kit enables robust, streamlined chromatin profiling of histone PTMs and chromatin proteins.

    Library Prep Kit

    The CUTANA™ Library Prep Kit features a specialized protocol optimized for high-sensitivity CUT&RUN applications.

    pAG-MNase

    A fusion of protein A, protein G and micrococcal nuclease selectively cleaves antibody-labelled chromatin in CUT&RUN.

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    Antibodies

    EpiCypher antibodies are validated with gold standard, application-specific approaches to ensure reliable results.

    Assay Controls

    Our rigorous controls enable workflow optimization, continuous assay monitoring, and aid in troubleshooting.

    Discover More

    Don’t stop there - explore other CUT&RUN related products, including magnetic racks, ConA beads, and our Nuclei Extraction Buffer.

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      • Products dropdown_arrow
      • Servicesdropdown_arrow
        • Services
        • CUTANA™ CUT&RUN Services
        • EpiDyne Chromatin Remodeling HTS assays
        • Custom Nucleosome Development Services
        • dCypher™ Assay Services For Novel Chromatin Interactions
        • SNAP-ChIP Antibody Validation Services
      • Technologiesdropdown_arrow
        • Technologies
        • CUTANA™ Assays Overview
        • CUTANA™ CUT&RUN Assays
        • CUTANA™ CUT&Tag Assays
        • CUTANA™ meCUT&RUN
        • CUTANA™ Multiomic CUT&RUN
        • SNAP Spike-in Controls
        • SNAP-Certified™ Antibodies
      • Resourcesdropdown_arrow
        • Resources
        • Education and Resourcesdropdown_arrow
          • Education and Resources
          • Blog
          • CUT&RUN Overview
          • Product References
          • Epigenetics Conferences
          • Scientific Posters
          • Product Brochures
          • EpiCypher 2025 Conference
        • Technical Supportdropdown_arrow
          • Technical Support
          • Manuals, Protocols, & Guides
          • Tech Support Center
          • Technical Notes (Tech Notes)
      • Aboutdropdown_arrow
        • About
        • About EpiCypher
        • Management
        • Board of Directors
        • Scientific Founders
        • Press Releases
        • Join Our Team
      • Contact Us
      • Terms of Use
      • Products
      • Nucleosomesdropdown_arrow
        • Nucleosomes
        • Recombinant Nucleosomes (Complete List)
        • SNAP-ChIP® Spike-ins
        • SNAP-CUTANA™ Spike-in Controls
        • Modified Designer Nucleosomes (dNucs™)
        • dCypher™ Nucleosome Panels
        • EpiDyne® Chromatin Remodeling Substrates
        • Recombinant Nucleosomes (rNucs)
        • Mutant Nucleosomes
        • Purified Nucleosomes (HeLa, Avian)
        • Nucleosome Components and Subunits
        • Variant Nucleosomes (vNucs)
        • Methyl DNA Designer Nucleosomes
      • Antibodiesdropdown_arrow
        • Antibodies
        • Antibodies (Complete List)
        • CUTANA™ CUT&RUN Antibodies
        • CUTANA™ CUT&Tag Antibodies
        • SNAP-ChIP® Certified Antibodies
      • Epigenetics Kits and Reagentsdropdown_arrow
        • Epigenetics Kits and Reagents
        • CUTANA™ ChIC / CUT&RUN Assays
        • CUTANA™ CUT&Tag Assays
      • DNA Methylation Sequencingdropdown_arrow
        • DNA Methylation Sequencing
        • CUTANA™ meCUT&RUN
        • CUTANA™ Multiomic CUT&RUN
      • Recombinant Proteinsdropdown_arrow
        • Recombinant Proteins
        • EpiDyne® Chromatin Remodeling Enzymes
        • Recombinant Histones
        • Histone Binding Domains
        • Modifying Enzymes
      • Otherdropdown_arrow
        • Other
        • IDEA Toolbox
        • Histone Peptides
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