SPRI bead or column DNA purification: Which method is best for CUT&RUN?
Purification of target-enriched DNA is central to CUT&RUN
(and CUT&Tag) chromatin mapping workflows. When considering a DNA…
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Improved controls for CUT&RUN profiling of epitope-tagged proteins
Protein tags have multiple uses and advantages in molecular biology1,2. They can improve protein stability
in vitro, streamline purificatio…
Nucleosome narratives: SMARCAL1-mediated tumor immune evasion
Senior author Alberto Ciccia, PhD (left) and first author Giuseppe Leuzzi, PhD.
In this new blog series, we are sitting down with the lead scie…
Top CUT&RUN and CUT&Tag chromatin mapping papers of 2023
2023 was a remarkable year for science. The first CRISPR-based gene therapy was approved in the U.K. and the U.S. for sickle-cell anemia,…
The promise of chromatin research to advance precision medicine
Precision medicine, also known as personalized or individualized medicine,
describes the use of patient-specific molecular features to guid…
How to select the best histone PTM antibody for CUT&RUN and CUT&Tag
EpiCypher’s CUTANA™
CUT&RUN
and
CUT&Tag
technologies are enabling major advancements in high-resolution profiling of
histone post…