dCypher™ Nucleosome Panels: Unparalleled Diversity for Rapid Histone PTM Profiling
Epigenetics is one of the fastest-growing areas of academic and pharmaceutical research, wit…
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SNAP-ChIP® Spike-In Controls are Essential for ChIP Experiments
Despite the overwhelming popularity of chromatin immunoprecipitation (ChIP) in epigenetics research, ChIP methods have…
EpiDyne®: Exploring Chromatin Remodeling Substrates with Nucleosomes
Nucleosomes are the fundamental repeating units of chromatin, comprised of a histone octamer wrapped by ~147bp DNA. A c…
Peptide or Nucleosome? dCypher™ Reveals the Optimal Substrate for Histone PTM Analyses
Histone ‘reader’ proteins contain evolutionarily conserved domains that bind to specific histone post-tra…
Why are designer nucleosomes so important for epigenetics research?
Nucleosome substrates are emerging tools for the in vitro study of chromatin epigenetic regulation, with applications from basic chromatin…