SKU: 15-0073
{"url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/yeats2-yeats-domain-recombinant-human","add_this":[{"service":"facebook","annotation":""},{"service":"email","annotation":""},{"service":"print","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"id":898,"bulk_discount_rates":[],"can_purchase":true,"meta_description":"Recombinant human protein YEATS2 YEATS Domain is useful for protein binding and screening experiments examining crotonylated protein substrates.","category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"AddThisServiceButtonMeta":"","main_image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/898/978/2c-CAD7g__13175.1646098022.png?c=2","alt":"YEATS2 YEATS Domain, Recombinant Human"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=898","shipping":{"calculated":true},"num_reviews":0,"weight":"0.01 LBS","custom_fields":[{"id":"1006","name":"Pack Size","value":"100 µg"}],"sku":"15-0073","description":"<div class=\"product-general-info\">\n <ul class=\"product-general-info__list-left\">\n <li class=\"product-general-info__list-item\">\n <strong>Type: </strong>YEATS\n </li>\n <li class=\"product-general-info__list-item\">\n <strong>Mol. Wgt.: </strong>18.9 kDa\n </li>\n </ul>\n <ul class=\"product-general-info__list-right\">\n <li class=\"product-general-info__list-item\">\n <strong>Expressed In : </strong><em>E. coli</em>\n </li>\n <li class=\"product-general-info__list-item\">\n <strong>Epitope Tag: </strong>His\n </li>\n </ul>\n</div>\n\n<div class=\"service_accordion product-droppdown\">\n <div class=\"container\">\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel current\">\n <h3 class=\"sub-title1\">Description</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description-specific\"\n >\n <p>\n YEATS2 YEATS Domain (accession Q9ULM3, amino acids 200-345)\n expressed in <em>E. coli</em> containing a C-terminal 6xHis tag. The\n YEATS2 protein is part of the ATAC complex, which has histone\n acetyltransferase activity on histones H3 and H4 [1]. YEATS2 YEATS\n Domain recognizes and binds H3K27cr [2].\n </p>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel current\">\n <h3 class=\"sub-title1\">Validation Data</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description-specific\"\n >\n <section class=\"image-picker\">\n <div class=\"image-picker__left\">\n <div\n class=\"image-picker__main-content_active image-picker__main-content\"\n >\n <div class=\"image-picker__header-content\">\n <button class=\"image-picker__left-arrow\">\n <svg\n class=\"image-picker__svg-left\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M16.67 0l2.83 2.829-9.339 9.175 9.339 9.167-2.83 2.829-12.17-11.996z\"\n />\n </svg>\n </button>\n <a\n href=\"/content/images/products/proteins/15-0073-protein-gel-data.jpeg\"\n target=\"_blank\"\n class=\"image-picker__main-image-link\"\n ><img\n alt=\"15-0073-protein-gel-data\"\n src=\"/content/images/products/proteins/15-0073-protein-gel-data.jpeg\"\n class=\"image-picker__main-image\"\n />\n <span class=\"image-picker__main-image-caption\"\n >(Click to enlarge)</span\n ></a\n >\n <button class=\"image-picker__right-arrow\">\n <svg\n class=\"image-picker__svg-right\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M7.33 24l-2.83-2.829 9.339-9.175-9.339-9.167 2.83-2.829 12.17 11.996z\"\n />\n </svg>\n </button>\n </div>\n <p>\n <span class=\"image-picker__span-content\"\n ><strong>Figure 1: Protein gel data </strong><br />\n YEATS2 YEATS Domain (1 µg) was resolved via PAGE gel and\n stained with Coomassie blue to demonstrate the size and\n purity of the protein. The migration and molecular weight of\n the protein standards are indicated.\n </span>\n </p>\n </div>\n <div class=\"image-picker__main-content\">\n <div class=\"image-picker__header-content\">\n <button class=\"image-picker__left-arrow\">\n <svg\n class=\"image-picker__svg-left\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M16.67 0l2.83 2.829-9.339 9.175 9.339 9.167-2.83 2.829-12.17-11.996z\"\n />\n </svg>\n </button>\n <a\n href=\"/content/images/products/proteins/15-0073-protein-interaction-data.jpeg\"\n target=\"_blank\"\n class=\"image-picker__main-image-link\"\n ><img\n alt=\"15-0073-protein-interaction-data\"\n src=\"/content/images/products/proteins/15-0073-protein-interaction-data.jpeg\"\n class=\"image-picker__main-image\"\n />\n <span class=\"image-picker__main-image-caption\"\n >(Click to enlarge)</span\n ></a\n >\n <button class=\"image-picker__right-arrow\">\n <svg\n class=\"image-picker__svg-right\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M7.33 24l-2.83-2.829 9.339-9.175-9.339-9.167 2.83-2.829 12.17 11.996z\"\n />\n </svg>\n </button>\n </div>\n <p>\n <span class=\"image-picker__span-content\"\n ><strong>Figure 2: Protein interaction data</strong><br />\n YEATS2 YEATS Domain demonstrates binding to H3K27cr peptide\n and no significant binding to H3(15-31) control peptide when\n analyzed by AlphaScreen<sup>®</sup> (PerkinElmer). All\n peptides assayed at 100 nM.\n </span>\n </p>\n </div>\n </div>\n <aside class=\"image-picker__right\">\n <div class=\"image-picker__gallery\">\n <img\n alt=\"15-0073-protein-gel-data\"\n src=\"/content/images/products/proteins/15-0073-protein-gel-data.jpeg\"\n width=\"200\"\n class=\"image-picker__side-image image-picker__side-image_active\"\n role=\"button\"\n />\n <img\n alt=\"15-0073-protein-interaction-data\"\n src=\"/content/images/products/proteins/15-0073-protein-interaction-data.jpeg\"\n class=\"image-picker__side-image\"\n role=\"button\"\n />\n </div>\n </aside>\n </section>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Technical Information</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <div class=\"product-tech-info\">\n <div class=\"product-tech-info__line-item\">\n <div class=\"product-tech-info__line-item-left\">\n <b>Formulation</b>\n </div>\n <div class=\"product-tech-info__line-item-right\">\n Recombinant 6xHis-tagged protein in 50mM HEPES pH 7.5, 500mM\n NaCl, 10% glycerol, 2mM TCEP.\n </div>\n </div>\n <div class=\"product-tech-info__line-item\">\n <div class=\"product-tech-info__line-item-left\">\n <b>Storage and Stability</b>\n </div>\n <div class=\"product-tech-info__line-item-right\">\n Stable for six months at -80°C from date of receipt. For\n best results, aliquot and avoid multiple freeze/thaws.\n </div>\n </div>\n </div>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Application Notes</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <p>\n YEATS2 YEATS Domain is useful for protein binding and screening\n experiments examining crotonylated protein substrates.\n </p>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">References</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <strong>Background References:</strong>\n <br />\n [1] Wang et al. <em>J Biol Chem</em> (2008). PMID:\n <a\n href=\"https://pubmed.ncbi.nlm.nih.gov/18838386/\"\n title=\"Human ATAC Is a GCN5/PCAF-containing acetylase complex with a novel NC2-like histone fold module that interacts with the TATA-binding protein\"\n target=\"new\"\n >\n 18838386</a\n ><br />\n [2] Zhao et al <em>Cell Res</em> (2016). PMID:\n <a\n href=\"https://pubmed.ncbi.nlm.nih.gov/27103431/\"\n title=\"YEATS2 is a selective histone crotonylation reader\"\n target=\"new\"\n >27103431</a\n ><br />\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Documents & Resources</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <div class=\"product-documents\">\n <a\n href=\"/content/documents/tds/15-0073.pdf\"\n target=\"_blank\"\n class=\"product-documents__link\"\n >\n <svg\n version=\"1.1\"\n id=\"Layer_1\"\n xmlns=\"http://www.w3.org/2000/svg\"\n xmlns:xlink=\"http://www.w3.org/1999/xlink\"\n x=\"0px\"\n y=\"0px\"\n viewBox=\"0 0 228 240\"\n style=\"enable-background: new 0 0 228 240\"\n xml:space=\"preserve\"\n class=\"product-documents__icon\"\n alt=\"16-0030 Datasheet\"\n >\n <g>\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M191.92,68.77l-47.69-47.69c-1.33-1.33-3.12-2.08-5.01-2.08H45.09C41.17,19,38,22.17,38,26.09v184.36\n c0,3.92,3.17,7.09,7.09,7.09h141.82c3.92,0,7.09-3.17,7.09-7.09V73.8C194,71.92,193.25,70.1,191.92,68.77z M177.65,77.06h-41.7\n v-41.7L177.65,77.06z M178.05,201.59H53.95V34.95h66.92v47.86c0,5.14,4.17,9.31,9.31,9.31h47.86V201.59z\"\n />\n </g>\n <rect\n x=\"20\"\n y=\"112\"\n class=\"product-documents__svg-background\"\n width=\"146\"\n height=\"76\"\n />\n <g>\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M23.83,125.68h22.36c5.29,0,9.41,1.33,12.35,4c2.94,2.67,4.42,6.39,4.42,11.18c0,4.78-1.47,8.51-4.42,11.18\n c-2.94,2.67-7.06,4-12.35,4H34.59v18.29H23.83V125.68z M44.81,147.9c5.38,0,8.07-2.32,8.07-6.97c0-2.39-0.67-4.16-2-5.31\n c-1.33-1.15-3.36-1.73-6.07-1.73H34.59v14.01H44.81z\"\n />\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M69.92,125.68h18.91c5.29,0,9.84,0.97,13.66,2.9c3.82,1.93,6.74,4.72,8.76,8.35\n c2.02,3.63,3.04,7.98,3.04,13.04c0,5.06-1,9.42-3,13.08c-2,3.66-4.91,6.45-8.73,8.38c-3.82,1.93-8.4,2.9-13.73,2.9H69.92V125.68z\n M88.07,165.63c10.35,0,15.52-5.22,15.52-15.66c0-10.4-5.17-15.59-15.52-15.59h-7.38v31.26H88.07z\"\n />\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M122.57,125.68h32.84v8.49h-22.22v11.18h20.84v8.49h-20.84v20.49h-10.63V125.68z\"\n />\n </g>\n </svg>\n <span class=\"product-documents__info\">Technical Datasheet</span>\n </a>\n </div>\n </div>\n </div>\n </div>\n </div>\n</div>\n","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$325.00","value":325,"currency":"USD"},"tax_label":"Sales Tax"},"detail_messages":"","availability":"","page_title":"YEATS2 YEATS Domain, Recombinant Human ","cart_url":"https://www.epicypher.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":null,"options":[],"related_products":[{"id":213,"sku":"15-0071","name":"AF9 YEATS Domain, Recombinant Human","url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/af9-yeats-domain-recombinant-human","availability":"","rating":null,"brand":{"name":null},"category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"summary":" ","image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/213/986/3vId-MiA__77761.1646104468.png?c=2","alt":"AF9 YEATS Domain, Recombinant Human"},"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/213/986/3vId-MiA__77761.1646104468.png?c=2","alt":"AF9 YEATS Domain, Recombinant Human"},{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/213/135/Me_Peptide_Binding-1__00927.1444238482.jpg?c=2","alt":"AF9 YEATS Domain, Recombinant Human"}],"date_added":"3rd Mar 2015","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":1125,"name":"Pack Size","value":"100 μg"},{"id":1126,"name":"Internal Comment","value":"new lot in bottom right of Pyslocke, included in inventory"}],"num_reviews":null,"weight":{"formatted":"0.01 LBS","value":0.01},"demo":false,"add_to_cart_url":"https://www.epicypher.com/cart.php?action=add&product_id=213","price":{"without_tax":{"currency":"USD","formatted":"$325.00","value":325},"tax_label":"Sales Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=213"},{"id":313,"sku":"15-0069","name":"ENL YEATS Domain, Recombinant Human","url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/enl-yeats-domain-recombinant-human","availability":"","rating":null,"brand":{"name":null},"category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"summary":" ","image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/313/987/3vId-MiA__88075.1646104494.png?c=2","alt":"ENL YEATS Domain, Recombinant Human"},"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/313/987/3vId-MiA__88075.1646104494.png?c=2","alt":"ENL YEATS Domain, Recombinant Human"},{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/313/213/Me_Peptide_Binding-1__08620.1444238482.1280.1280__11435.1456435606.1280.1280__92285.1456435716.1280.1280__83731.1478545904.jpg?c=2","alt":"ENL YEATS Domain, Recombinant Human"}],"date_added":"4th Aug 2016","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":1098,"name":"Pack Size","value":"100 μg"},{"id":1099,"name":"Internal Comment","value":"1 unit left, with special peptide terminus"},{"id":1100,"name":"Internal Comment","value":"41 units of lot 6 in New Lot Rack in Psylocke, included in count"}],"num_reviews":null,"weight":{"formatted":"0.01 LBS","value":0.01},"demo":false,"add_to_cart_url":"https://www.epicypher.com/cart.php?action=add&product_id=313","price":{"without_tax":{"currency":"USD","formatted":"$325.00","value":325},"tax_label":"Sales Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=313"},{"id":899,"sku":"15-0075","name":"GAS41 YEATS Domain, Recombinant Human","url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/gas41-yeats-domain-recombinant-human","availability":"","rating":null,"brand":{"name":null},"category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"summary":"\n \n \n Type: YEATS\n \n \n Mol. Wgt.: 19.3 kDa\n \n \n \n ","image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/899/979/2c-CAD7g__64065.1646099563.png?c=2","alt":"GAS41 YEATS Domain, Recombinant Human"},"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/899/979/2c-CAD7g__64065.1646099563.png?c=2","alt":"GAS41 YEATS Domain, Recombinant Human"}],"date_added":"1st Mar 2022","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":1007,"name":"Pack Size","value":"100 µg"}],"num_reviews":null,"weight":{"formatted":"0.01 LBS","value":0.01},"demo":false,"add_to_cart_url":"https://www.epicypher.com/cart.php?action=add&product_id=899","price":{"without_tax":{"currency":"USD","formatted":"$325.00","value":325},"tax_label":"Sales Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=899"},{"id":335,"sku":"15-0070","name":"ENL YEATS Domain, Y78A, Recombinant 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","image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/246/332/Human_recombinant_nucleosome__44913.1516390310.gif?c=2","alt":"Mononucleosomes, Recombinant Human"},"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/246/332/Human_recombinant_nucleosome__44913.1516390310.gif?c=2","alt":"Mononucleosomes, Recombinant Human"}],"date_added":"20th Oct 2015","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":1302,"name":"Pack Size","value":"100 μg"},{"id":1303,"name":"Internal Comment","value":"Bulk in LG"},{"id":1304,"name":"Internal Comment","value":"Additional Units Bottom Right of Psylocke"}],"num_reviews":null,"weight":{"formatted":"0.01 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Pack Size: 100 µg
