SKU: 15-0075
{"url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/gas41-yeats-domain-recombinant-human","add_this":[{"service":"facebook","annotation":""},{"service":"email","annotation":""},{"service":"print","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"id":899,"bulk_discount_rates":[],"can_purchase":true,"meta_description":"Recombinant human protein Gas41 YEATS Domain is useful for protein binding and screening experiments examining acetylated and crotonylated protein substrates.","category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"AddThisServiceButtonMeta":"","main_image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/899/979/2c-CAD7g__64065.1646099563.png?c=2","alt":"GAS41 YEATS Domain, Recombinant Human"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=899","shipping":{"calculated":true},"num_reviews":0,"weight":"0.01 LBS","custom_fields":[{"id":"1007","name":"Pack Size","value":"100 µg"}],"sku":"15-0075","description":"<div class=\"product-general-info\">\n <ul class=\"product-general-info__list-left\">\n <li class=\"product-general-info__list-item\">\n <strong>Type: </strong>YEATS\n </li>\n <li class=\"product-general-info__list-item\">\n <strong>Mol. Wgt.: </strong>19.3 kDa\n </li>\n </ul>\n <ul class=\"product-general-info__list-right\">\n <li class=\"product-general-info__list-item\">\n <strong>Expressed In : </strong><em>E. coli</em>\n </li>\n <li class=\"product-general-info__list-item\">\n <strong>Epitope Tag: </strong>His\n </li>\n </ul>\n</div>\n\n<div class=\"service_accordion product-droppdown\">\n <div class=\"container\">\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel current\">\n <h3 class=\"sub-title1\">Description</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description-specific\"\n >\n <p>\n GAS41 YEATS Domain (accession O95619, amino acids 15-160) expressed\n in <em>E. coli</em> containing an N-terminal 6xHis tag. The GAS41\n protein is part of the NuA4 histone acetyltransferase complex, which\n is involved with the activation of genes via acetylation of histones\n H4 and H2A [1]. GAS41 YEATS Domain recognizes and binds acetylated\n and crotonylated histone H3 [2].\n </p>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel current\">\n <h3 class=\"sub-title1\">Validation Data</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description-specific\"\n >\n <section class=\"image-picker\">\n <div class=\"image-picker__left\">\n <div\n class=\"image-picker__main-content_active image-picker__main-content\"\n >\n <div class=\"image-picker__header-content\">\n <button class=\"image-picker__left-arrow\">\n <svg\n class=\"image-picker__svg-left\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M16.67 0l2.83 2.829-9.339 9.175 9.339 9.167-2.83 2.829-12.17-11.996z\"\n />\n </svg>\n </button>\n <a\n href=\"/content/images/products/proteins/15-0075-protein-gel-data.jpeg\"\n target=\"_blank\"\n class=\"image-picker__main-image-link\"\n ><img\n alt=\"15-0075-protein-gel-data\"\n src=\"/content/images/products/proteins/15-0075-protein-gel-data.jpeg\"\n class=\"image-picker__main-image\"\n />\n <span class=\"image-picker__main-image-caption\"\n >(Click to enlarge)</span\n ></a\n >\n <button class=\"image-picker__right-arrow\">\n <svg\n class=\"image-picker__svg-right\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M7.33 24l-2.83-2.829 9.339-9.175-9.339-9.167 2.83-2.829 12.17 11.996z\"\n />\n </svg>\n </button>\n </div>\n <p>\n <span class=\"image-picker__span-content\"\n ><strong>Figure 1: Protein gel data </strong><br />\n GAS41 YEATS Domain (1 µg) was resolved via PAGE gel and\n stained with Coomassie blue to demonstrate the size and\n purity of the protein. The migration and molecular weight of\n the protein standards are indicated.\n </span>\n </p>\n </div>\n <div class=\"image-picker__main-content\">\n <div class=\"image-picker__header-content\">\n <button class=\"image-picker__left-arrow\">\n <svg\n class=\"image-picker__svg-left\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M16.67 0l2.83 2.829-9.339 9.175 9.339 9.167-2.83 2.829-12.17-11.996z\"\n />\n </svg>\n </button>\n <a\n href=\"/content/images/products/proteins/15-0075-protein-interaction-data.jpeg\"\n target=\"_blank\"\n class=\"image-picker__main-image-link\"\n ><img\n alt=\"15-0075-protein-interaction-data\"\n src=\"/content/images/products/proteins/15-0075-protein-interaction-data.jpeg\"\n class=\"image-picker__main-image\"\n />\n <span class=\"image-picker__main-image-caption\"\n >(Click to enlarge)</span\n ></a\n >\n <button class=\"image-picker__right-arrow\">\n <svg\n class=\"image-picker__svg-right\"\n width=\"24\"\n height=\"24\"\n viewBox=\"0 0 24 24\"\n >\n <path\n d=\"M7.33 24l-2.83-2.829 9.339-9.175-9.339-9.167 2.83-2.829 12.17 11.996z\"\n />\n </svg>\n </button>\n </div>\n <p>\n <span class=\"image-picker__span-content\"\n ><strong>Figure 2: Protein interaction data</strong><br />\n GAS41 YEATS Domain demonstrates preferential binding to\n H3K9cr, followed by H3K9,14,18cr and H3K9ac. There was no\n significant binding to H3(1-20) control peptide when\n analyzed by AlphaScreen<sup>®</sup> (PerkinElmer). All\n peptides assayed at 100 nM.\n </span>\n </p>\n </div>\n </div>\n <aside class=\"image-picker__right\">\n <div class=\"image-picker__gallery\">\n <img\n alt=\"15-0075-protein-gel-data\"\n src=\"/content/images/products/proteins/15-0075-protein-gel-data.jpeg\"\n width=\"200\"\n class=\"image-picker__side-image image-picker__side-image_active\"\n role=\"button\"\n />\n <img\n alt=\"15-0075-protein-interaction-data\"\n src=\"/content/images/products/proteins/15-0075-protein-interaction-data.jpeg\"\n class=\"image-picker__side-image\"\n role=\"button\"\n />\n </div>\n </aside>\n </section>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Technical Information</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <div class=\"product-tech-info\">\n <div class=\"product-tech-info__line-item\">\n <div class=\"product-tech-info__line-item-left\">\n <b>Formulation</b>\n </div>\n <div class=\"product-tech-info__line-item-right\">\n Recombinant 6xHis-tagged protein in 20mM Tris HCl pH 7.5, 500mM\n NaCl, 5% glycerol, 1 mM DTT.\n </div>\n </div>\n <div class=\"product-tech-info__line-item\">\n <div class=\"product-tech-info__line-item-left\">\n <b>Storage and Stability</b>\n </div>\n <div class=\"product-tech-info__line-item-right\">\n Stable for six months at -80°C from date of receipt. For\n best results, aliquot and avoid multiple freeze/thaws.\n </div>\n </div>\n </div>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Application Notes</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <p>\n GAS41 YEATS Domain is useful for protein binding and screening\n experiments examining acetylated and crotonylated protein\n substrates.\n </p>\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">References</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <strong>Background References:</strong>\n <br />\n [1] Doyon et al. <em>Mol Cell Biol</em> (2004). PMID:\n <a\n href=\"https://pubmed.ncbi.nlm.nih.gov/14966270/\"\n title=\"Structural and functional conservation of the NuA4 histone acetyltransferase complex from yeast to humans\"\n target=\"new\"\n >\n 14966270</a\n ><br />\n [2] Cho et al <em>ACS Chem Biol</em> (2018). PMID:\n <a\n href=\"https://pubmed.ncbi.nlm.nih.gov/30071723/\"\n title=\"GAS41 Recognizes Diacetylated Histone H3 through a Bivalent Binding Mode\"\n target=\"new\"\n >30071723</a\n ><br />\n </div>\n </div>\n </div>\n <div id=\"prodAccordion\">\n <div id=\"ProductDescription\" class=\"Block Panel\">\n <h3 class=\"sub-title1\">Documents & Resources</h3>\n <div\n class=\"ProductDescriptionContainer product-droppdown__section-description\"\n >\n <div class=\"product-documents\">\n <a\n href=\"/content/documents/tds/15-0075.pdf\"\n target=\"_blank\"\n class=\"product-documents__link\"\n >\n <svg\n version=\"1.1\"\n id=\"Layer_1\"\n xmlns=\"http://www.w3.org/2000/svg\"\n xmlns:xlink=\"http://www.w3.org/1999/xlink\"\n x=\"0px\"\n y=\"0px\"\n viewBox=\"0 0 228 240\"\n style=\"enable-background: new 0 0 228 240\"\n xml:space=\"preserve\"\n class=\"product-documents__icon\"\n alt=\"16-0030 Datasheet\"\n >\n <g>\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M191.92,68.77l-47.69-47.69c-1.33-1.33-3.12-2.08-5.01-2.08H45.09C41.17,19,38,22.17,38,26.09v184.36\n c0,3.92,3.17,7.09,7.09,7.09h141.82c3.92,0,7.09-3.17,7.09-7.09V73.8C194,71.92,193.25,70.1,191.92,68.77z M177.65,77.06h-41.7\n v-41.7L177.65,77.06z M178.05,201.59H53.95V34.95h66.92v47.86c0,5.14,4.17,9.31,9.31,9.31h47.86V201.59z\"\n />\n </g>\n <rect\n x=\"20\"\n y=\"112\"\n class=\"product-documents__svg-background\"\n width=\"146\"\n height=\"76\"\n />\n <g>\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M23.83,125.68h22.36c5.29,0,9.41,1.33,12.35,4c2.94,2.67,4.42,6.39,4.42,11.18c0,4.78-1.47,8.51-4.42,11.18\n c-2.94,2.67-7.06,4-12.35,4H34.59v18.29H23.83V125.68z M44.81,147.9c5.38,0,8.07-2.32,8.07-6.97c0-2.39-0.67-4.16-2-5.31\n c-1.33-1.15-3.36-1.73-6.07-1.73H34.59v14.01H44.81z\"\n />\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M69.92,125.68h18.91c5.29,0,9.84,0.97,13.66,2.9c3.82,1.93,6.74,4.72,8.76,8.35\n c2.02,3.63,3.04,7.98,3.04,13.04c0,5.06-1,9.42-3,13.08c-2,3.66-4.91,6.45-8.73,8.38c-3.82,1.93-8.4,2.9-13.73,2.9H69.92V125.68z\n M88.07,165.63c10.35,0,15.52-5.22,15.52-15.66c0-10.4-5.17-15.59-15.52-15.59h-7.38v31.26H88.07z\"\n />\n <path\n class=\"product-documents__svg-pdf\"\n d=\"M122.57,125.68h32.84v8.49h-22.22v11.18h20.84v8.49h-20.84v20.49h-10.63V125.68z\"\n />\n </g>\n </svg>\n <span class=\"product-documents__info\">Technical Datasheet</span>\n </a>\n </div>\n </div>\n </div>\n </div>\n </div>\n</div>\n","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$325.00","value":325,"currency":"USD"},"tax_label":"Sales Tax"},"detail_messages":"","availability":"","page_title":"Gas41 YEATS Domain, Recombinant Human ","cart_url":"https://www.epicypher.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":null,"options":[],"related_products":[{"id":213,"sku":"15-0071","name":"AF9 YEATS Domain, Recombinant Human","url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/af9-yeats-domain-recombinant-human","availability":"","rating":null,"brand":{"name":null},"category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"summary":" ","image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/213/986/3vId-MiA__77761.1646104468.png?c=2","alt":"AF9 YEATS Domain, Recombinant Human"},"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/213/986/3vId-MiA__77761.1646104468.png?c=2","alt":"AF9 YEATS Domain, Recombinant Human"},{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/213/135/Me_Peptide_Binding-1__00927.1444238482.jpg?c=2","alt":"AF9 YEATS Domain, Recombinant Human"}],"date_added":"3rd Mar 2015","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":1125,"name":"Pack Size","value":"100 μg"},{"id":1126,"name":"Internal Comment","value":"new lot in bottom right of Pyslocke, included in inventory"}],"num_reviews":null,"weight":{"formatted":"0.01 LBS","value":0.01},"demo":false,"add_to_cart_url":"https://www.epicypher.com/cart.php?action=add&product_id=213","price":{"without_tax":{"currency":"USD","formatted":"$325.00","value":325},"tax_label":"Sales Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=213"},{"id":313,"sku":"15-0069","name":"ENL YEATS Domain, Recombinant Human","url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/enl-yeats-domain-recombinant-human","availability":"","rating":null,"brand":{"name":null},"category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"summary":" ","image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/313/987/3vId-MiA__88075.1646104494.png?c=2","alt":"ENL YEATS Domain, Recombinant Human"},"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/313/987/3vId-MiA__88075.1646104494.png?c=2","alt":"ENL YEATS Domain, Recombinant Human"},{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/313/213/Me_Peptide_Binding-1__08620.1444238482.1280.1280__11435.1456435606.1280.1280__92285.1456435716.1280.1280__83731.1478545904.jpg?c=2","alt":"ENL YEATS Domain, Recombinant Human"}],"date_added":"4th Aug 2016","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":1098,"name":"Pack Size","value":"100 μg"},{"id":1099,"name":"Internal Comment","value":"1 unit left, with special peptide terminus"},{"id":1100,"name":"Internal Comment","value":"41 units of lot 6 in New Lot Rack in Psylocke, included in count"}],"num_reviews":null,"weight":{"formatted":"0.01 LBS","value":0.01},"demo":false,"add_to_cart_url":"https://www.epicypher.com/cart.php?action=add&product_id=313","price":{"without_tax":{"currency":"USD","formatted":"$325.00","value":325},"tax_label":"Sales Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=313"},{"id":898,"sku":"15-0073","name":"YEATS2 YEATS Domain, Recombinant Human","url":"https://www.epicypher.com/products/recombinant-proteins/histone-binding-domains/yeats2-yeats-domain-recombinant-human","availability":"","rating":null,"brand":{"name":null},"category":["Recombinant Proteins/Histone Binding Domains","Recombinant Proteins/Histone Binding Domains/YEATS Domain Proteins"],"summary":"\n \n \n Type: YEATS\n \n \n Mol. Wgt.: 18.9 kDa\n \n \n \n ","image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/898/978/2c-CAD7g__13175.1646098022.png?c=2","alt":"YEATS2 YEATS Domain, Recombinant Human"},"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/898/978/2c-CAD7g__13175.1646098022.png?c=2","alt":"YEATS2 YEATS Domain, Recombinant Human"}],"date_added":"1st Mar 2022","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":1006,"name":"Pack Size","value":"100 µg"}],"num_reviews":null,"weight":{"formatted":"0.01 LBS","value":0.01},"demo":false,"add_to_cart_url":"https://www.epicypher.com/cart.php?action=add&product_id=898","price":{"without_tax":{"currency":"USD","formatted":"$325.00","value":325},"tax_label":"Sales Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=898"},{"id":335,"sku":"15-0070","name":"ENL YEATS Domain, Y78A, Recombinant 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2017","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":172,"name":"Pack Size","value":"100 μg"}],"num_reviews":null,"weight":{"formatted":"0.01 LBS","value":0.01},"demo":false,"add_to_cart_url":"https://www.epicypher.com/cart.php?action=add&product_id=335","price":{"without_tax":{"currency":"USD","formatted":"$325.00","value":325},"tax_label":"Sales Tax"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=335"},{"id":246,"sku":"16-0009","name":"Mononucleosomes, Recombinant Human","url":"https://www.epicypher.com/products/nucleosomes/mononucleosomes-recombinant-human","availability":"","rating":null,"brand":{"name":null},"category":["Nucleosomes","Nucleosomes/Recombinant Nucleosomes (rNucs)"],"summary":"\n \n \n Species: Human\n \n \n Source: E. coli & synthetic DNA\n \n \n \n ","image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/246/332/Human_recombinant_nucleosome__44913.1516390310.gif?c=2","alt":"Mononucleosomes, Recombinant Human"},"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/246/332/Human_recombinant_nucleosome__44913.1516390310.gif?c=2","alt":"Mononucleosomes, Recombinant Human"}],"date_added":"20th Oct 2015","pre_order":false,"show_cart_action":true,"has_options":false,"stock_level":null,"low_stock_level":null,"qty_in_cart":0,"custom_fields":[{"id":1302,"name":"Pack Size","value":"100 μg"},{"id":1303,"name":"Internal Comment","value":"Bulk in LG"},{"id":1304,"name":"Internal Comment","value":"Additional Units Bottom Right of Psylocke"}],"num_reviews":null,"weight":{"formatted":"0.01 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Pack Size: 100 µg
