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EpiDyne® Chromatin Remodeling Substrates
Chromatin remodeling has been implicated in diverse diseases, including most types of cancer. The study of chromatin remodeling requires highly defined nucleosomal substrates, which are challenging to produce and adapt to various assays. The EpiDyne® platform addresses this unmet need, leveraging EpiCypher dNucs™ as substrates for a variety of nucleosome remodeling assays.
EpiDyne substrates are suitable for various chromatin remodeling assays
- EpiDyne-FRET: HTS compatible, ideal for compound screening
- EpiDyne-PicoGreen: proprietary method, enables high throughput at low cost
- Restriction Enzyme Accessibility (REA) also supported
- Full details and protocols available in User Guide
Learn more:
- EpiDyne Brochure
- Getting started with EpiDyne? Read the User Guide
- Learn about EpiDyne applications on our Blog
- How do we quantify our nucleosomes? See our Nucleosome Quantification Method
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