Variant Nucleosomes (vNucs)

Histone variants are important to many cellular processes, including DNA replication, DNA repair, and transcription. EpiCypher variant nucleosomes (vNucs) are assembled with defined variant histones, providing a physiological substrate for the functional analysis of noncanonical nucleosomes.

Shop vNucs

Three ways to leverage vNucs for chromatin research

Use as substrates for testing for inhibitors
Study effects of variant histone on enzyme activity
Test specificity of antibody

Learn more:

Need vNucs that carry other epigenomic features? Check out our custom nucleosome services
dCypher nucleosome binding assays are ideal for studying chromatin interactions – learn more
EpiCypher has developed nucleosomes for multiple applications – read our brochure