EpiDyne^® Chromatin Remodeling Enzymes

ATP-dependent chromatin remodeling enzymes are among the most commonly mutated proteins in cancer, making them a top target for the development of novel therapeutic strategies. The EpiDyne® platform leverages EpiCypher dNucs as substrates to study nucleosome remodeling. To complement these assays, EpiCypher offers a range of remodeling enzymes, including SMARCA2 and SMARCA4 (the ATPases of the SWI/SNF complex) and the ACF ISWI-type complex.

Shop EpiDyne Remodeling Enzymes

EpiDyne Chromatin Remodeling Enzymes can be used in various assays:

EpiDyne-FRET: HTS compatible
EpiDyne-PicoGreen: low cost, high throughput format
Restriction Enzyme Accessibility (EpiDyne-REA) assays
See full enzyme descriptions and applications in the User Guide

Learn more:

Getting started with EpiDyne? Check out the User Guide
EpiDyne Brochure
Read more about the EpiDyne platform on the EpiCypher Blog!

Shop related products and services:

SMARCA5 Chromatin Remodeling Enzyme (Human SNF2H)

SKU: 15-1024

Full length recombinant human SMARCA5 Remodeling Enzyme. SMARCA5 is a core ATPase subunit of the ATP-dependent chromatin remodeling ISWI complexes that regulate nucleosome spac...

$405.00

SMARCA4 Chromatin Remodeling Enzyme (Human BRG1)

SKU: 15-1014

$575.00

SMARCA2 Chromatin Remodeling Enzyme (Human BRM)

SKU: 15-1015

Full length recombinant human SMARCA2 Remodeling Enzyme. SMARCA2 is a core ATPase subunit of the ATP-dependent chromatin remodeling complex SWI/SNF that mobilizes nucleosomes a...

$575.00

SMARCA5 Chromatin Remodeling Enzyme (Human SNF2H)

SMARCA4 Chromatin Remodeling Enzyme (Human BRG1)

SMARCA2 Chromatin Remodeling Enzyme (Human BRM)

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