Histone CENP-A / H4 Tetramer, Recombinant Human
$160.00
SKU: 16-0010
{"url":"https://www.epicypher.com/products/nucleosomes/histone-cenp-a-h4-tetramer-recombinant-human","add_this":[{"service":"facebook","annotation":""},{"service":"email","annotation":""},{"service":"print","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"options":[],"id":262,"bulk_discount_rates":[],"can_purchase":true,"meta_description":"Histone CENP-A/H4 Tetramer, Recombinant Human for Chromatin Reconstitution and Enzyme Screening","category":["Nucleosomes","Nucleosomes/Nucleosome Components and Subunits","Recombinant Proteins/Recombinant Histones"],"AddThisServiceButtonMeta":"","main_image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/262/1037/epi_sg_fullcolor_rgb__84525.1659389317.png?c=2","alt":"Histone CENP-A / H4 Tetramer, Recombinant Human"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=262","shipping":{"calculated":true},"num_reviews":0,"weight":"0.01 LBS","custom_fields":[{"id":"135","name":"Pack Size","value":"50 μg"}],"sku":"16-0010","description":"<div>\n<table border=\"0\" cellpadding=\"2\" cellspacing=\"2\" width=\"100%\">\n\t<tbody>\n\t\t<tr valign=\"top\">\n\t\t\t<td>\n\t\t\t<table border=\"0\" cellpadding=\"1\" cellspacing=\"1\" width=\"95%\">\n\t\t\t\t<tbody>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td>\n\t\t\t\t\t\t<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\">\n\t\t\t\t\t\t\t<tbody>\n\t\t\t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t<td align=\"left\" valign=\"top\"><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Type: </b>Histone</span></span></td>\n\t\t\t\t\t\t\t\t\t<td align=\"left\" valign=\"top\"><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Host: </b><em>E. coli</em></span></span></td>\n\t\t\t\t\t\t\t\t</tr>\n\t\t\t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t<td align=\"left\" valign=\"top\"><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Mol Wgt.: </b>54 kDa</span></span></td>\n\t\t\t\t\t\t\t\t\t<td align=\"left\" valign=\"top\"><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Epitope Tag: </b>None</span></span></td>\n\t\t\t\t\t\t\t\t</tr>\n\t\t\t\t\t\t\t</tbody>\n\t\t\t\t\t\t</table>\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\">\n\t\t\t\t\t\t<span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Histone CENP-A/H4 Tetramers, Recombinant Human Description:</b> CENP-A/ Histone H4 Tetramers made from recombinant histones expressed in <em>E. coli</em> (Centromere protein A, CENPA, CenH3; accession numbers: CENP-A: P49450; H4: P62805). CENP-A and H4 were expressed and purified individually by FPLC, then assembled into tetramers that were further purified using gel filtration chromatography. CENP-A is a specialized variant of H3 and component of modified nucleosomes found at the core centromere.</span></span><br />\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Histone CENP-A/H4 Tetramers, Recombinant Human Formulation:</b> 50 µg of CENP-A/H4 Tetramer in 40mM sodium phosphate buffer pH 7.0, 1M NaCl, 7mM β-ME, 50% glycerol.</span></span><br />\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Histone CENP-A/H4 Tetramers, Recombinant Human Storage and Stability:</b> Stable for 6 months at -20°C .</span></span><br />\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\">\n\t\t\t\t\t\t<p><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Histone CENP-A/H4 Tetramers, Recombinant Human Application Notes:</b> Recombinant histone CENP-A/H4 Tetramers are suitable for enzyme assays and nucleosome reconstitution.</span></span></p>\n\n\t\t\t\t\t\t<p style=\"text-align: center;\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><span style=\"color:#FF0000;\"><strong>N.B DO NOT FREEZE. DO NOT STORE AT -80°C</strong></span></span></span></p>\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><strong style=\"font-size: 12pt;\">References:</strong><br />\n\t\t\t\t\t\tSekulic N et al (2010). <em>Nature</em> 476: 347-351. <a href=\"http://www.ncbi.nlm.nih.gov/pubmed/20739937\" target=\"_new\">Link</a><br />\n\t\t\t\t\t\tFalk SJ et al (2015). <em>Science</em> 348: 699-703. <a href=\"http://www.ncbi.nlm.nih.gov/pubmed/25954010\" target=\"_new\">Link</a></span></span><br />\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\">View technical datasheet for this product. <a href=\"/content/documents/tds/16-0010.pdf\" target=\"_new\"> <img alt=\"16-0010 Datasheet\" height=\"40\" src=\"/content/documents/tds/icon.png\" width=\"30\" /></a></span></span></td>\n\t\t\t\t\t</tr>\n\t\t\t\t</tbody>\n\t\t\t</table>\n\t\t\t</td>\n\t\t\t<td>\n\t\t\t<table border=\"0\" cellpadding=\"3\" cellspacing=\"3\" width=\"100%\">\n\t\t\t\t<tbody>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td align=\"center\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><a href=\"/content/images/products/proteins/16_0010_gel_tds.jpg\" target=\"_new\"><img alt=\"16-0010 Gel and Purity QC Data\" height=\"250\" src=\"/content/images/products/proteins/16_0010_gel_tds.jpg\" width=\"114\" /></a></span></span></td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td align=\"left\" valign=\"top\">\n\t\t\t\t\t\t<p><span style=\"font-size:10pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><strong>QC Protein Data:</strong> Histone CENP-A/H4 Tetramers, Recombinant Human, (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated.<br />\n\t\t\t\t\t\t<strong>(Click image to enlarge) </strong></span></span></p>\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t</tbody>\n\t\t\t</table>\n\t\t\t</td>\n\t\t</tr>\n\t</tbody>\n</table>\n</div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$160.00","value":160,"currency":"USD"},"tax_label":"Sales Tax"},"detail_messages":"","availability":"","page_title":"Histone CENP-A/H4 Tetramer, Recombinant Human","cart_url":"https://www.epicypher.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":null,"shipping_messages":[],"rating":0,"meta_keywords":"Histone CENP-A/H4 Tetramer, Recombinant Human","show_quantity_input":1,"title":"Histone CENP-A / H4 Tetramer, Recombinant Human","gift_wrapping_available":false,"min_purchase_quantity":0,"customizations":[],"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/262/1037/epi_sg_fullcolor_rgb__84525.1659389317.png?c=2","alt":"Histone CENP-A / H4 Tetramer, Recombinant Human"}]} Pack Size: 50 μg
{"url":"https://www.epicypher.com/products/nucleosomes/histone-cenp-a-h4-tetramer-recombinant-human","add_this":[{"service":"facebook","annotation":""},{"service":"email","annotation":""},{"service":"print","annotation":""},{"service":"twitter","annotation":""},{"service":"linkedin","annotation":""}],"gtin":null,"options":[],"id":262,"bulk_discount_rates":[],"can_purchase":true,"meta_description":"Histone CENP-A/H4 Tetramer, Recombinant Human for Chromatin Reconstitution and Enzyme Screening","category":["Nucleosomes","Nucleosomes/Nucleosome Components and Subunits","Recombinant Proteins/Recombinant Histones"],"AddThisServiceButtonMeta":"","main_image":{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/262/1037/epi_sg_fullcolor_rgb__84525.1659389317.png?c=2","alt":"Histone CENP-A / H4 Tetramer, Recombinant Human"},"add_to_wishlist_url":"/wishlist.php?action=add&product_id=262","shipping":{"calculated":true},"num_reviews":0,"weight":"0.01 LBS","custom_fields":[{"id":"135","name":"Pack Size","value":"50 μg"}],"sku":"16-0010","description":"<div>\n<table border=\"0\" cellpadding=\"2\" cellspacing=\"2\" width=\"100%\">\n\t<tbody>\n\t\t<tr valign=\"top\">\n\t\t\t<td>\n\t\t\t<table border=\"0\" cellpadding=\"1\" cellspacing=\"1\" width=\"95%\">\n\t\t\t\t<tbody>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td>\n\t\t\t\t\t\t<table border=\"0\" cellpadding=\"0\" cellspacing=\"0\" width=\"100%\">\n\t\t\t\t\t\t\t<tbody>\n\t\t\t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t<td align=\"left\" valign=\"top\"><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Type: </b>Histone</span></span></td>\n\t\t\t\t\t\t\t\t\t<td align=\"left\" valign=\"top\"><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Host: </b><em>E. coli</em></span></span></td>\n\t\t\t\t\t\t\t\t</tr>\n\t\t\t\t\t\t\t\t<tr>\n\t\t\t\t\t\t\t\t\t<td align=\"left\" valign=\"top\"><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Mol Wgt.: </b>54 kDa</span></span></td>\n\t\t\t\t\t\t\t\t\t<td align=\"left\" valign=\"top\"><span style=\"font-size:11pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Epitope Tag: </b>None</span></span></td>\n\t\t\t\t\t\t\t\t</tr>\n\t\t\t\t\t\t\t</tbody>\n\t\t\t\t\t\t</table>\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\">\n\t\t\t\t\t\t<span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Histone CENP-A/H4 Tetramers, Recombinant Human Description:</b> CENP-A/ Histone H4 Tetramers made from recombinant histones expressed in <em>E. coli</em> (Centromere protein A, CENPA, CenH3; accession numbers: CENP-A: P49450; H4: P62805). CENP-A and H4 were expressed and purified individually by FPLC, then assembled into tetramers that were further purified using gel filtration chromatography. CENP-A is a specialized variant of H3 and component of modified nucleosomes found at the core centromere.</span></span><br />\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Histone CENP-A/H4 Tetramers, Recombinant Human Formulation:</b> 50 µg of CENP-A/H4 Tetramer in 40mM sodium phosphate buffer pH 7.0, 1M NaCl, 7mM β-ME, 50% glycerol.</span></span><br />\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Histone CENP-A/H4 Tetramers, Recombinant Human Storage and Stability:</b> Stable for 6 months at -20°C .</span></span><br />\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\">\n\t\t\t\t\t\t<p><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><b>Histone CENP-A/H4 Tetramers, Recombinant Human Application Notes:</b> Recombinant histone CENP-A/H4 Tetramers are suitable for enzyme assays and nucleosome reconstitution.</span></span></p>\n\n\t\t\t\t\t\t<p style=\"text-align: center;\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><span style=\"color:#FF0000;\"><strong>N.B DO NOT FREEZE. DO NOT STORE AT -80°C</strong></span></span></span></p>\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><strong style=\"font-size: 12pt;\">References:</strong><br />\n\t\t\t\t\t\tSekulic N et al (2010). <em>Nature</em> 476: 347-351. <a href=\"http://www.ncbi.nlm.nih.gov/pubmed/20739937\" target=\"_new\">Link</a><br />\n\t\t\t\t\t\tFalk SJ et al (2015). <em>Science</em> 348: 699-703. <a href=\"http://www.ncbi.nlm.nih.gov/pubmed/25954010\" target=\"_new\">Link</a></span></span><br />\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td valign=\"top\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\">View technical datasheet for this product. <a href=\"/content/documents/tds/16-0010.pdf\" target=\"_new\"> <img alt=\"16-0010 Datasheet\" height=\"40\" src=\"/content/documents/tds/icon.png\" width=\"30\" /></a></span></span></td>\n\t\t\t\t\t</tr>\n\t\t\t\t</tbody>\n\t\t\t</table>\n\t\t\t</td>\n\t\t\t<td>\n\t\t\t<table border=\"0\" cellpadding=\"3\" cellspacing=\"3\" width=\"100%\">\n\t\t\t\t<tbody>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td align=\"center\"><span style=\"font-size:12pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><a href=\"/content/images/products/proteins/16_0010_gel_tds.jpg\" target=\"_new\"><img alt=\"16-0010 Gel and Purity QC Data\" height=\"250\" src=\"/content/images/products/proteins/16_0010_gel_tds.jpg\" width=\"114\" /></a></span></span></td>\n\t\t\t\t\t</tr>\n\t\t\t\t\t<tr>\n\t\t\t\t\t\t<td align=\"left\" valign=\"top\">\n\t\t\t\t\t\t<p><span style=\"font-size:10pt;\"><span style=\"font-family:arial,helvetica,sans-serif;\"><strong>QC Protein Data:</strong> Histone CENP-A/H4 Tetramers, Recombinant Human, (1 µg) was run on a PAGE gel and stained with Coomassie blue. The migration and molecular weight of the protein standards are indicated.<br />\n\t\t\t\t\t\t<strong>(Click image to enlarge) </strong></span></span></p>\n\t\t\t\t\t\t</td>\n\t\t\t\t\t</tr>\n\t\t\t\t</tbody>\n\t\t\t</table>\n\t\t\t</td>\n\t\t</tr>\n\t</tbody>\n</table>\n</div>","tags":[],"warranty":"","price":{"without_tax":{"formatted":"$160.00","value":160,"currency":"USD"},"tax_label":"Sales Tax"},"detail_messages":"","availability":"","page_title":"Histone CENP-A/H4 Tetramer, Recombinant Human","cart_url":"https://www.epicypher.com/cart.php","max_purchase_quantity":0,"mpn":null,"upc":null,"shipping_messages":[],"rating":0,"meta_keywords":"Histone CENP-A/H4 Tetramer, Recombinant Human","show_quantity_input":1,"title":"Histone CENP-A / H4 Tetramer, Recombinant Human","gift_wrapping_available":false,"min_purchase_quantity":0,"customizations":[],"images":[{"data":"https://cdn11.bigcommerce.com/s-y9o92/images/stencil/{:size}/products/262/1037/epi_sg_fullcolor_rgb__84525.1659389317.png?c=2","alt":"Histone CENP-A / H4 Tetramer, Recombinant Human"}]} Pack Size: 50 μg
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