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    • Nucleosomes
    • SNAP-ChIP<sup>®</sup> Spike-ins

    SNAP-ChIP® Spike-ins

    SNAP-ChIP® Spike-in panels use modified DNA-barcoded Designer Nucleosomes (dNucs™) carrying disease-relevant histone PTMs as quantitative controls and for antibody validation, enabling unprecedented control of ChIP experiments.

    Shop SNAP-ChIP Spike-ins

    Three ways SNAP-ChIP spike-ins improve ChIP
    • Identify and/or validate PTM-specific antibody (see our recent paper in Molecular Cell)
    • In situ monitoring of ChIP performance (read our Blog for more)
    • Quantitative normalization (click here and here for some great examples!)
    Learn more:
    • Learn the basics of SNAP-ChIP Spike-ins here!
    • SNAP-ChIP Brochure
    • Why should you use SNAP-ChIP for antibody validation? Read our feature at Nature.com.
    • How can SNAP-ChIP spike-ins improve ChIP? Read about it on the EpiCypher Blog!
    • How do we quantify our nucleosomes? See our Nucleosome Quantification Method
    Shop related products and services:
    • SNAP-ChIP Certified Antibodies
    SNAP-ChIP® K-MetStat Panel
    SNAP-ChIP® K-MetStat Panel

    View
    $365.00
    SNAP-ChIP® K-AcylStat Panel
    SNAP-ChIP® K-AcylStat Panel

    View
    $365.00
    SNAP-ChIP® OncoStat Panel
    SNAP-ChIP® OncoStat Panel

    View
    $365.00
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      • Products dropdown_arrow
      • Servicesdropdown_arrow
        • Services
        • CUTANA™ CUT&RUN Services
        • EpiDyne Chromatin Remodeling HTS assays
        • Custom Nucleosome Development Services
        • dCypher™ Assay Services For Novel Chromatin Interactions
        • SNAP-ChIP Antibody Validation Services
      • Technologiesdropdown_arrow
        • Technologies
        • CUTANA™ Assays Overview
        • CUTANA™ CUT&RUN Assays
        • CUTANA™ CUT&Tag Assays
        • CUTANA™ meCUT&RUN
        • CUTANA™ Multiomic CUT&RUN
        • SNAP Spike-in Controls
        • SNAP-Certified™ Antibodies
      • Resourcesdropdown_arrow
        • Resources
        • Education and Resourcesdropdown_arrow
          • Education and Resources
          • Blog
          • CUT&RUN Overview
          • Product References
          • Epigenetics Conferences
          • Scientific Posters
          • Product Brochures
          • EpiCypher 2025 Conference
        • Technical Supportdropdown_arrow
          • Technical Support
          • Manuals, Protocols, & Guides
          • Tech Support Center
          • Technical Notes (Tech Notes)
      • Aboutdropdown_arrow
        • About
        • About EpiCypher
        • Management
        • Board of Directors
        • Scientific Founders
        • Press Releases
        • Join Our Team
      • Contact Us
      • Terms of Use
      • Products
      • Nucleosomesdropdown_arrow
        • Nucleosomes
        • Recombinant Nucleosomes (Complete List)
        • SNAP-ChIP® Spike-ins
        • SNAP-CUTANA™ Spike-in Controls
        • Modified Designer Nucleosomes (dNucs™)
        • dCypher™ Nucleosome Panels
        • EpiDyne® Chromatin Remodeling Substrates
        • Recombinant Nucleosomes (rNucs)
        • Mutant Nucleosomes
        • Purified Nucleosomes (HeLa, Avian)
        • Nucleosome Components and Subunits
        • Variant Nucleosomes (vNucs)
        • Methyl DNA Designer Nucleosomes
      • Antibodiesdropdown_arrow
        • Antibodies
        • Antibodies (Complete List)
        • CUTANA™ CUT&RUN Antibodies
        • CUTANA™ CUT&Tag Antibodies
        • SNAP-ChIP® Certified Antibodies
      • Epigenetics Kits and Reagentsdropdown_arrow
        • Epigenetics Kits and Reagents
        • CUTANA™ ChIC / CUT&RUN Assays
        • CUTANA™ CUT&Tag Assays
      • Recombinant Proteinsdropdown_arrow
        • Recombinant Proteins
        • EpiDyne® Chromatin Remodeling Enzymes
        • Recombinant Histones
        • Histone Binding Domains
        • Modifying Enzymes
      • Otherdropdown_arrow
        • Other
        • IDEA Toolbox
        • Histone Peptides
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